Actively Recruiting
Prebiotics and the Management of Hyperuricemia
Led by Sun Yat-sen University · Updated on 2024-06-05
160
Participants Needed
2
Research Sites
137 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hyperuricemia is a major risk factor for many chronic diesease. Recently, gut mcirobiota has been identified as a novel theraputic target for hyperuricemia. Both annimal studies and pilot human trials have demonstrated that administration of prebiotics help delay the progression of hyperuricemia throuh several mechanisms. This trial aims to examine its protective effects and potential mechanisms in clinical trials.
CONDITIONS
Official Title
Prebiotics and the Management of Hyperuricemia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Local residents aged between 18 and 80 years old
- Stable body weight with less than 5% change over the past 3 months
- Fasting uric acid level higher than 420 umol/L for males and higher than 360 umol/L for females on two separate days
- Not currently taking uric acid lowering drugs or have stopped these drugs at least 4 weeks before recruitment
- No use of diet or medication that could affect uric acid metabolism or gut microbiota, including antibiotics, prebiotics, or probiotics, for at least 4 weeks before recruitment
You will not qualify if you...
- Having acute illness or signs of any acute or chronic inflammatory or infectious diseases
- Participating in a regular diet program more than twice per week in the past 3 months before recruitment
- Having mental illness that impairs understanding of the study's nature, scope, and possible consequences
- Women of childbearing age who are pregnant, breastfeeding, or planning to become pregnant
- Having had surgery in the past 6 months or planning surgery during the trial period
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Department of Nutrition and Food Hygiene
Guangzhou, Guangdong, China, 510080
Actively Recruiting
2
Sun Yat-Sen University
Guangzhou, Guangdong, China, 510080
Actively Recruiting
Research Team
Y
Yan Liu, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
4
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