Actively Recruiting

Phase 4
Age: 18Years - 80Years
All Genders
NCT06269432

Precise Antiplatelet THerapy Guided by Platelet Aggregation Function in Ischemic STROKE(PATH-STROKE)

Led by Sichuan Provincial People's Hospital · Updated on 2025-06-26

1020

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

1. Main objective: To explore the efficacy of precise antiplatelet therapy guided by platelet aggregation function in reducing the incidence of 30 day platelet hyperresponsiveness in patients with non-cardiogenic ischemic stroke. 2. Secondary objective: To explore the efficacy and safety of antiplatelet therapy in patients with non-cardiogenic ischemic stroke under the guidance of platelet aggregation function.

CONDITIONS

Official Title

Precise Antiplatelet THerapy Guided by Platelet Aggregation Function in Ischemic STROKE(PATH-STROKE)

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged from 18 to 80 years
  • Diagnosed with non-cardiogenic ischemic stroke confirmed by cranial CT or MRI
  • First stroke onset between 1 and 3 months ago
  • Modified Rankin Scale (mRS) score of 2 or less
  • Taking 100 mg aspirin daily for at least 8 days
  • Signed informed consent by patient or family member
Not Eligible

You will not qualify if you...

  • History of recurrent stroke
  • History of gastrointestinal bleeding, intracranial hemorrhage, or other bleeding disorders
  • Contraindications or intolerance to antiplatelet medications
  • Severe heart, lung, liver, or kidney failure, or serious other illnesses such as advanced cancer or organ failure
  • Poor compliance or inability to cooperate with the study requirements

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sichuan Provincial People's Hospital

Chengdu, Sichuan, China, 610072

Actively Recruiting

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Research Team

J

Jie Yang, doctor

CONTACT

Y

YaPeng Lin, doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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