Actively Recruiting
Precision Adjuvant Therapy After Surgery for Hepatocellular Carcinoma
Led by Chen Xiaoping · Updated on 2024-05-07
300
Participants Needed
1
Research Sites
247 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Vessels that encapsulate tumor clusters (VETC) is an invasive metastatic factor in HCC independent of the epithelial mesenchyme transition (EMT), and VETC-positive patients have a higher rate of postoperative recurrence. How to improve the prognosis of this group of patients is an urgent issue to be addressed.
CONDITIONS
Official Title
Precision Adjuvant Therapy After Surgery for Hepatocellular Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years
- No previous local or systemic treatment for hepatocellular carcinoma
- Child-Pugh liver function score of 7 or less
- ECOG performance status of 0 or 1
- No serious organic diseases of the heart, lungs, brain, kidneys, or other major organs
- Pathologic diagnosis of hepatocellular carcinoma
- Confirmed presence of VETC vascular pattern by CD34 immunohistochemical staining
You will not qualify if you...
- Pregnant or breastfeeding women
- Conditions affecting absorption, distribution, metabolism, or clearance of study drugs (such as severe vomiting, chronic diarrhea, intestinal obstruction, impaired absorption)
- History of gastrointestinal bleeding within 4 weeks or known risk factors for gastrointestinal bleeding not treated
- Active infection
- Significant clinical or laboratory abnormalities affecting safety evaluation
- Inability to follow study protocol for treatment or scheduled follow-up
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
Wuhan, Hubei, China, 430000
Actively Recruiting
Research Team
W
WanGuang Zhang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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