Actively Recruiting
Precision Analytic Research Methods in OCD
Led by Icahn School of Medicine at Mount Sinai · Updated on 2025-10-23
100
Participants Needed
1
Research Sites
246 weeks
Total Duration
On this page
Sponsors
I
Icahn School of Medicine at Mount Sinai
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Psychiatric disorders characterized by compulsivity, such as obsessive-compulsive disorder (OCD), result in considerable functional impairment and many individuals do not respond to gold-standard treatments. Compulsivity has long been thought to occur due to exaggerated habits and reduced goal-directed control, although more recently, this conceptualization of compulsivity as an imbalance of two cognitive systems has been challenged as overly narrow. This study will recruit 100 individuals (50 adults diagnosed with OCD, 50 healthy controls) and leverage the measurement precision offered by theory-driven computational modeling in combination with electroencephalogram (EEG) to go beyond this binary theory of compulsivity, revealing how more complex interactions of neurocognitive subcomponents contribute to compulsivity-information that could ultimately lead to improved treatment personalization and clinical outcomes.
CONDITIONS
Official Title
Precision Analytic Research Methods in OCD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between the ages 18 and 55 years old
- English-speaking
- Right-handed
- Able to provide consent
You will not qualify if you...
- Diagnosed with certain other psychiatric disorders
- Taking psychiatric medication or received behavioral treatment for OCD within a certain timeframe
- Unsafe to participate in research
- For healthy controls: current psychiatric disorder
- For healthy controls: lifetime history of certain psychiatric disorders
- For healthy controls: taking psychiatric medication currently or in the past
- For healthy controls: parent or sibling diagnosed with OCD
- Unsafe to participate in research
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Icahn School of Medicine at Mount Sinai
New York, New York, United States, 10029
Actively Recruiting
Research Team
A
Amy Rapp, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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