Actively Recruiting
Precision Biomarkers to Detect Brain Injury in Active-Duty United States Special Operations Forces With Repeated Blast Exposure
Led by Massachusetts General Hospital · Updated on 2025-10-31
100
Participants Needed
1
Research Sites
202 weeks
Total Duration
On this page
Sponsors
M
Massachusetts General Hospital
Lead Sponsor
U
University of South Florida
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a 4-year, longitudinal study of 100 active-duty Navy SEALs. The goal of the study is to determine whether repeated blast exposure affects SEAL brain health and to develop an initial diagnostic testing protocol that detects repeated blast brain injury.
CONDITIONS
Official Title
Precision Biomarkers to Detect Brain Injury in Active-Duty United States Special Operations Forces With Repeated Blast Exposure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Active-duty Navy SEAL service member
- Early career SEAL (0-2 years) or mid-late career SEAL (10-15 years)
- Male, aged 18 to 50 years
You will not qualify if you...
- History of moderate or severe traumatic brain injury
- History of major neurological disorder
- Untreated or unstable severe psychiatric condition
- Current severe medical condition requiring long-term treatment
- Any condition causing undue risk or logistical issues
- Contraindication to MRI
- Contraindication to PET scan
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
Research Team
B
Brian L Edlow, M.D.
CONTACT
M
Michael A Gordon, B.s.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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