Actively Recruiting
Precision Diagnosis and Prospective Cohort Study for Myasthenia Gravis: Multicenter Analysis in China
Led by Huashan Hospital · Updated on 2025-05-28
500
Participants Needed
4
Research Sites
221 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The present study is a prospective cohort study aiming to improve the clinical capacity in the diagnosis and natural history of Chinese patients with myasthenia gravis (MG). 300 MG patients are planned to recruit, document and prospectively follow up. Management of screening test and cohort manifestation are studied.
CONDITIONS
Official Title
Precision Diagnosis and Prospective Cohort Study for Myasthenia Gravis: Multicenter Analysis in China
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Fluctuating muscle weakness and tiredness, along with at least one of the following:
- More than 10% decrease in amplitude during low frequency repetitive nerve stimulation or less than 10% increase during high frequency repetitive nerve stimulation
- Positive anti-AChR or MuSK antibody test
- Positive neostigmine test
- Ability to understand and provide informed consent and comply with follow-up visits
You will not qualify if you...
- Diagnoses other than MG such as Lambert-Eaton syndrome, congenital myasthenia syndrome, botulism injection, chronic progressive external ophthalmoplegia
- Poor compliance with follow-up requirements
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 4 locations
1
Shanghai Chest Hospital
Shanghai, Shanghai Municipality, China, 200000
Actively Recruiting
2
Obsterics and Gynecology Hospital of Fudan University
Shanghai, Shanghai Municipality, China, 200011
Actively Recruiting
3
Children's Hospital of Fudan University
Shanghai, Shanghai Municipality, China, 201102
Actively Recruiting
4
Huashan Hospital
Shanghai, China, 200040
Actively Recruiting
Research Team
C
Chongbo Zhao, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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