Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID05857995

Precision Lung Cancer Survivorship Care Intervention: A Randomized Controlled Trial Serving Rural Survivors and Communities

Led by Jerod L Stapleton, PhD · Updated on 2026-02-23

300

Participants Needed

1

Research Sites

39 weeks

Total Duration

On this page

Sponsors

J

Jerod L Stapleton, PhD

Lead Sponsor

U

University of Louisville

Collaborating Sponsor

AI-Summary

What this Trial Is About

Lung cancer is a leading cause of death, especially in rural areas like Kentucky where incidence and mortality rates are very high. This research evaluates a new lung cancer survivorship care program designed to improve quality of life, reduce stigma, and increase engagement with care among lung cancer survivors. The study is a randomized controlled trial comparing this program to an enhanced usual care approach, aiming to benefit rural survivors facing significant challenges. The trial compares two groups: one receives the Kentucky LEADS Collaborative Lung Cancer Survivorship Care Program (KLCLCSC), which is a tailored behavioral intervention focusing on patient-centered care, shared decision making, and motivational interviewing. The other group receives enhanced usual care, which includes standard care plus bibliotherapy and assessment. The study will include 300 lung cancer survivors recruited from ten oncology centers in Kentucky. Participants will be monitored over six months, with assessments at the start and end of this period. Researchers will measure changes in lung cancer quality of life using the FACT-L tool, as well as survivor engagement, symptom burden, psychological well-being, and behavior changes. The study also examines the impact of caregiver involvement and evaluates the cost-effectiveness of the new program. The total duration and follow-up are designed to capture important outcomes related to survivorship care.

CONDITIONS

Brief Title

Precision Lung Cancer Survivorship Care Intervention

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have been diagnosed with lung cancer
  • Reside in a rural county as determined by a Rural Urban Continuum Code (RUC) of 4 or higher
  • Be at least 18 years of age or older
  • Be able to communicate effectively in English
Not Eligible

You will not qualify if you...

  • Have significant psychiatric disturbance that requires a higher level of care
  • Have substance abuse/dependence that requires a higher level of care
  • Are participating in another lung cancer survivorship care intervention
  • Have previously participated in the Kentucky LEADS Lung Cancer Survivorship Care Program

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 6 months

Participants receive either the Kentucky LEADS Collaborative Lung Cancer Survivorship Care Program or enhanced usual care to improve lung cancer quality of life and engagement.

Baseline visit and follow-up visits during the 6-month intervention period

Follow-up

Duration - Up to 6 months from baseline

Participants are monitored to assess changes in quality of life, symptom burden, psychosocial well-being, and behavior at 6 months post-baseline.

Follow-up visit at 6 months

Trial Site Locations

Total: 1 location

1

Markey Cancer Center

Lexington, Kentucky, United States, 40536

Actively Recruiting

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Research Team

J

Jerod L Stapleton, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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