Actively Recruiting

Age: 30Years - 70Years
MALE
NCT04763317

Precision Medicine in the Prostate Cancer Care Pathway

Led by Institute of Cancer Research, United Kingdom · Updated on 2025-12-16

3000

Participants Needed

1

Research Sites

824 weeks

Total Duration

On this page

Sponsors

I

Institute of Cancer Research, United Kingdom

Lead Sponsor

R

Royal Marsden NHS Foundation Trust

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aims to evaluate the use of a prostate cancer specific predisposition genetic panel test in men with / at high risk of prostate cancer. The genetic test will analyse men's DNA samples for the presence of mutations in rare genes as well as common genetic variation to provide men with information about their risk of prostate cancer. This study will evaluate the clinical impact of the test on risk assessment and clinical management in terms of screening and treatment.

CONDITIONS

Official Title

Precision Medicine in the Prostate Cancer Care Pathway

Who Can Participate

Age: 30Years - 70Years
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Men aged between 30 and 70 years
  • Diagnosed with prostate cancer before age 60 or
  • Diagnosed with metastatic castration resistant prostate cancer at any age or aggressive prostate cancer with Gleason score 4+4 or higher under 70 years
  • Have a family history of prostate cancer defined as three or more cases in first or second degree relatives at any age
Not Eligible

You will not qualify if you...

  • WHO performance status 4

AI-Screening

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Trial Site Locations

Total: 1 location

1

Royal Marsden Hosital,

Sutton, England, United Kingdom, SM2 5PT

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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