Actively Recruiting
Precision Medicine for Stem Cell Transplantation
Led by University of Manchester · Updated on 2025-04-03
300
Participants Needed
3
Research Sites
269 weeks
Total Duration
On this page
Sponsors
U
University of Manchester
Lead Sponsor
T
The Christie NHS Foundation Trust
Collaborating Sponsor
AI-Summary
What this Trial Is About
A study of patients undergoing haematopoietic stem cell transplantation, a procedure in which patients are infused with stem cells from a donor, resulting in a new immune system that eliminates cancer or replaces diseased bone marrow. This study aims to develop new blood tests that predict the onset of acute graft-versus-host disease (aGvHD) and leukaemia relapse, two life-threatening complications that frequently limit the success of treatment. Predictive tests would allow doctors to individualise prophylaxis and intervene early to abort complications before they develop. The study will also create a large collection of clinically annotated blood samples from 300 transplant recipients to support future research and provide a resource to the transplant research community.
CONDITIONS
Official Title
Precision Medicine for Stem Cell Transplantation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Recipient of allogeneic haematopoietic stem cell transplantation
- No age restriction; children and infants may participate
- Participation in other clinical trials is allowed
You will not qualify if you...
- Weight less than 5 kilograms
- Recipient of autologous stem cell transplantation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Manchester Royal Infirmary
Manchester, United Kingdom, m13 9wl
Actively Recruiting
2
Royal Manchester Children's Hospital
Manchester, United Kingdom, m139wl
Actively Recruiting
3
The Christie NHS Foundation Trust
Manchester, United Kingdom, M20 4BX
Actively Recruiting
Research Team
M
Mark Williams
CONTACT
A
Abbey Walker
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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