Actively Recruiting
The Precision Nutrition New York Study
Led by Cornell University · Updated on 2025-07-11
15
Participants Needed
1
Research Sites
50 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Dietary fiber has been shown to have beneficial effects on human health through its impact on microbes present in the gut. However, these effects can vary between individuals, and everyone may not reap the same health benefits by eating the same sources of fiber. Factors predicting how an individual's gut microbes as well as the beneficial metabolites produced by these microbes change in response to different sources of fiber would be helpful in developing precision nutrition approaches that maximize the benefits of dietary fiber. The objective of this study is to evaluate candidate predictors of gut microbiota response to fiber sources from either whole grains or fruits and vegetables.
CONDITIONS
Official Title
The Precision Nutrition New York Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age is between 21-50 years
- BMI is between 25-30
- Able to have height, weight, waist, and hip circumference, and body composition measured during the study
- Able to provide saliva samples
- Able to provide a phone number and email address for study contact
- Able to increase dietary fiber intake to recommended levels following USDA MyPlate instructions
- Able to provide food records of all consumed items on one weekday and one weekend day weekly using an online survey
- Able to provide 10 stool samples over 11 weeks
- Stable weight within plus or minus 3% of usual body weight for the last two months
- Able to take an online survey to assess recent dietary fiber intake for eligibility
You will not qualify if you...
- Has an electronic medical implant such as a pacemaker
- Has an existing, untreated thyroid condition
- Used systemic antibiotics in the last 4 months
- Has an acute disease at enrollment, defined as moderate or severe illness with or without fever
- Has a chronic, clinically significant pulmonary, cardiovascular, gastrointestinal, hepatic, or renal functional abnormality requiring ongoing management
- Suspected immunosuppression or immunodeficiency including HIV
- Has a history of active untreated gastrointestinal disorders including inflammatory bowel disease, ulcerative colitis, Crohn's or celiac disease, indeterminate colitis, moderate to severe irritable bowel syndrome, persistent infectious gastroenteritis, chronic diarrhea of unknown cause, recurrent Clostridium difficile infection, or chronic constipation
- Previously had bariatric surgery
- Has had major diet changes in the last month, such as eliminating or greatly increasing a major food group
- Has a recent history of chronic alcohol use exceeding 5 drinks per day
- Female participants who are pregnant or lactating
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cornell University
Ithaca, New York, United States, 14850
Actively Recruiting
Research Team
A
Angela Poole
CONTACT
C
Colette Strathman
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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