Actively Recruiting
PRecision Oncology CUhk pRogrammE (PRO-CURE)
Led by Brigette Ma · Updated on 2024-08-22
200
Participants Needed
1
Research Sites
376 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main aim of this project is to establish an innovative model of a comprehensive precision oncology platform to help individualizing drug therapy for patients with advanced cancers at The Chinese University of Hong Kong. The other objectives include to optimize the genomic matching and access of patients with unique cancer subtypes to the relevant clinical trials of novel therapies, and to construct a personalized drug screening platform for individuals using novel cancer models established from patient-derived cancer cells and tissues. Other objectives include to investigate the utility and feasibility of genomic sequencing using circulating tumor DNA(ctDNA), and to establish a biobank of tumor tissues derived from patients with unique cancer subtypes.
CONDITIONS
Official Title
PRecision Oncology CUhk pRogrammE (PRO-CURE)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 18 to 75 years
- ECOG performance status of 0 to 1
- Histologically or cytologically confirmed cancers of certain subtype
- Medically fit for systemic therapy in palliative, neoadjuvant, adjuvant, or concurrent radiotherapy settings
- Limited systemic therapeutic options and candidates for clinical trials
- Able to give written informed consent
- Willing to have blood samples taken
- Availability of an archived paraffin-embedded tumor block
You will not qualify if you...
- Refusal or medical unfitness for systemic therapy
- More than one invasive cancer diagnosed in the last five years
- No measurable tumor lesions on radiological imaging
- Unable to give written informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Chinese University of Hong Kong
Hong Kong, Hong Kong
Actively Recruiting
Research Team
B
Brigette MA, MD
CONTACT
A
Alice KONG, PC
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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