Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04814095

PRecision Oncology Evidence Development in Cancer Treatment - Clinical: PREDiCTc

Led by British Columbia Cancer Agency · Updated on 2025-09-25

30

Participants Needed

1

Research Sites

356 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This pilot clinical trial aims to assess the real world quality of life and survival of patients treated with targeted therapy that has preliminary evidence of efficacy in subjects with advanced rare cancers or cancer harbouring rare molecular aberrations. The treatment has been granted conditional or full approved by Health Canada (HC) as effective and safe. Due to the rarity of the cancer or molecular aberration the uncertainty level of the health technology assessment (HTA) by the pan Canadian Oncology Review (pCODR) was too high for consideration of funding or it was not submitted for consideration. Consequently, the goal of this study is to generate real world evidence to support HTA decision making throughout the life cycle of the product.

CONDITIONS

Official Title

PRecision Oncology Evidence Development in Cancer Treatment - Clinical: PREDiCTc

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older at the time of consent
  • Diagnosed with an incurable malignancy with rare cancer type or rare molecular aberration
  • Currently receiving Health Canada approved targeted therapy not nationally funded
  • ECOG performance status of 0 to 2
  • Life expectancy of at least 12 weeks
  • Adequate blood and organ function for drug treatment as assessed by clinician
  • Asymptomatic or treated brain metastases allowed
  • Ability to give informed consent for study procedures
Not Eligible

You will not qualify if you...

  • Treatment with any approved or investigational agent or participation in another therapeutic clinical trial within 14 days before enrollment
  • Unable to complete quality of life questionnaires
  • Considered unfit by treating clinician to participate in this protocol

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

BC Cancer

Vancouver, British Columbia, Canada, V5Z4E6

Actively Recruiting

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Research Team

S

Samantha Pollard, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

1

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