Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05554133

Precision Optical Guidance for Oral Biopsy

Led by M.D. Anderson Cancer Center · Updated on 2026-04-16

90

Participants Needed

1

Research Sites

197 weeks

Total Duration

On this page

Sponsors

M

M.D. Anderson Cancer Center

Lead Sponsor

N

National Institute of Dental and Craniofacial Research (NIDCR)

Collaborating Sponsor

AI-Summary

What this Trial Is About

To learn if a new type of imaging device called the Active Biopsy Guidance System can help doctors to decide when and where to perform invasive biopsies of mouth lesions.

CONDITIONS

Official Title

Precision Optical Guidance for Oral Biopsy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult subjects with visible oral lesions such as leukoplakia or erythroplakia, oral potentially malignant disorders like lichen planus or graft vs. host disease, diagnosed dysplasia, squamous cell carcinoma, or history of oral cancer surgery are eligible
  • Patients with prior treatments including surgery, radiation, chemotherapy, or other therapies can participate
  • Ability to understand and sign a written informed consent document
Not Eligible

You will not qualify if you...

  • Known allergy to proflavine or acriflavine
  • Age less than 18 years
  • Pregnant or nursing females
  • Adults unable to give consent
  • Prisoners and other vulnerable populations

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

M D Anderson Cancer Center

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

A

Ann Gillenwater, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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