Actively Recruiting
Precision Palliative Care for Patients With Advanced Esophageal Cancer
Led by Fudan University · Updated on 2026-01-13
624
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if precision palliative care improves survival of patients with advanced esophageal cancer in adults. Researchers will compare precision palliative care and standard palliative care to see if precision palliative care works more effectively to treat advanced esophageal s cancer. Participants will receive precision palliative care or standard palliative care. All participants will answer survey questions about their quality of life, MDASI, PHQ-9, GAD-7 for 1 years.
CONDITIONS
Official Title
Precision Palliative Care for Patients With Advanced Esophageal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Provide written informed consent
- Be aged 18 years or older
- Have histologically confirmed esophageal cancer
- Have clinical stage IV or recurrent esophageal cancer based on the 8th AJCC TNM classification
- Plan to be treated with anti-PD-1/PD-L1 immunotherapy
- Have an ECOG performance status of 0 to 2
- Have adequate organ function including specified blood counts and liver and kidney function tests
You will not qualify if you...
- Have esophageal perforation or hematemesis
- Have any active autoimmune disease or a history of autoimmune disease, or require immunosuppressive agents or systemic hormonal therapy within 28 days (except for adverse events of chemoradiotherapy)
- Have disease progression within 3 months after anti-PD-1/PD-L1 immunotherapy
- Be allergic to macromolecular protein preparations or any ingredients in anti-PD-1/PD-L1 inhibitors
- Have uncontrolled heart diseases or clinical symptoms such as NYHA class II or higher heart failure, unstable angina, myocardial infarction within 1 year, or clinically significant arrhythmia requiring intervention
- Have congenital or acquired immunodeficiency, active hepatitis B or C, or active tuberculosis
- Have active infection or unexplained fever over 38.5 °C within 2 weeks before randomization (except tumor-related fever)
- Be unwilling to use contraceptive measures if fertile, or be pregnant or breastfeeding
- Have other serious diseases, mental illness, or social factors that may affect safety or data collection, as determined by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fudan University
Shanghai, Shanghai Municipality, China, 200032
Actively Recruiting
Research Team
K
Kuaile Zhao, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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