Actively Recruiting

Phase Not Applicable
Age: 55Years - 70Years
All Genders
NCT07523061

PrecisionAge Pilot Study

Led by Heike A. Bischoff-Ferrari, Prof. Dr. med., DrPH · Updated on 2026-05-04

10

Participants Needed

1

Research Sites

3 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a pilot trial to test the feasibility of a multimodal lifestyle intervention (physical activity, mindfulness, sleep routines, calorie-restricted Mediterranean diet, supplements: vitamin D, omega-3, Multivitamin-mineral Centrum50+®, plant-based-supplement Fruitflow®) in preparation of a larger clinical trial.

CONDITIONS

Official Title

PrecisionAge Pilot Study

Who Can Participate

Age: 55Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Community-dwelling women and men aged between 55 and 70 years
  • Low daily exercise (less than 4000 steps per day on average in the last month, self-assessed)
  • Low fruit and vegetable intake (less than 3 servings per day)
  • At risk for accelerated functional and biological aging based on overweight (BMI 25.0 to 29.9) or related lab/blood pressure criteria
  • HbA1c between 5.7 and 6.4% (pre-diabetes) or LDL 3.4 to 4.1 mmol/L or triglycerides above 1.7 mmol/L (atherogenesis) or hs-CRP 2 to 3 mg/L (low-grade inflammation) or borderline blood pressure (SBP 130-139 / DBP 85-89 mmHg)
  • Availability of a smartphone and consent to use it with an activity tracker and data upload
  • Ability to communicate, read, and write in German
  • Dietary tolerability of a Mediterranean diet
  • Ability to swallow supplement capsules
Not Eligible

You will not qualify if you...

  • Current smoking or vaping (defined by lifetime or recent history)
  • Current supplementation with vitamin D, omega-3, Fruitflow, Centrum Silver Adults 50+, or other multivitamins and unwillingness to stop during the trial
  • Prior use over 3 months or current use of metformin, GLP-1, or SGLT-2 inhibitors
  • Current or recent (last 12 months) participation in another clinical trial or plans to participate
  • Diagnosed cancer (except non-melanoma skin cancer) in last 4 years
  • History of myocardial infarction, stroke, transient ischemic attack, angina pectoris, or coronary artery intervention in last 4 years
  • Renal impairment or liver disease
  • Severe mobility impairment preventing exercise participation
  • Major visual or hearing impairment
  • Other serious illness that would prevent participation
  • Living with another study participant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Universitäre Altersmedizin Felix Platter

Basel, Canton of Basel-City, Switzerland, 4055

Actively Recruiting

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Research Team

H

Heike A Bischoff-Ferrari, Prof. Dr. med., DrPH

CONTACT

M

Michèle Mattle, Dr. sc. med.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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