Actively Recruiting
Preclinical Research for Personalized TCR-T Therapy for Head and Neck Cancer
Led by Eye & ENT Hospital of Fudan University · Updated on 2023-01-26
100
Participants Needed
1
Research Sites
173 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will obtain tumor samples from patients with head and neck cancers and aims to develop personalized TCR-T therapy for head and neck cancer by determining the reactive TCR clone sequences in head and neck cancer.
CONDITIONS
Official Title
Preclinical Research for Personalized TCR-T Therapy for Head and Neck Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Gender is not limited, age 18-75 years old
- Estimated survival is greater than 3 months
- Newly diagnosed patients with head and neck cancer without any treatment, or patients with refractory recurrent advanced head and neck cancer with no effective treatment
- Patients with head and neck cancer whose tumor tissue can be surgically harvested
- Volunteer to join the study and sign the informed consent
You will not qualify if you...
- Infected or had been infected with COVID-19
- Active hepatitis B or C virus, HIV infection, or other uncured active infections
- Patients who received PD-1 or other immune checkpoint inhibitors within 8 weeks before surgery
- Patients who had chemotherapy drugs within 8 weeks before surgery
- Patients who had hormone drug use within 4 weeks before surgery
- Other situations deemed inappropriate for trial inclusion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Eye & ENT Hospital of Fudan University
Shanghai, Shanghai Municipality, China, 200031
Actively Recruiting
Research Team
J
Jian Chen, Ph.D
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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