Actively Recruiting
Preconception Intervention for Incarcerated Women With Substance Use
Led by St. Louis University · Updated on 2025-07-22
90
Participants Needed
1
Research Sites
169 weeks
Total Duration
On this page
Sponsors
S
St. Louis University
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this pilot trial is to test the feasibility and acceptability as well as efficacy of the adapted intervention, CHOICES-PLEAS (Pregnancy Liberated from Exposure to Alcohol and Substances) among women will illicit polysubstance use participating in a court-mandated jail-based 90-day substance use disorder treatment program. The main questions it aims to answer are: 1. What is the feasibility and acceptability of implementing the CHOICES-PLEAS intervention in a court-mandated jail-based substance use disorder treatment program? 2. Does participation in CHOICES-PLEAS lower the risk of a substance exposed pregnancy at 1 and 3 months after release compared to a control condition? 3. Does participation in CHOICES-PLEAS increase motivation to change substance use and reduce risky sexual behaviors at 1 and 3 months after release compared to a control condition? Participants will receive three one-on-one motivational interviewing sessions and one family planning referral visit during incarceration and one booster session at 1 month after release from jail. Researchers will compare the CHOICES-PLEAS intervention to a control condition to see if participation in the intervention reduces risk of substance exposed pregnancy, increases motivation to change substance use, and reduces risk of risky sexual behaviors.
CONDITIONS
Official Title
Preconception Intervention for Incarcerated Women With Substance Use
Who Can Participate
Eligibility Criteria
You may qualify if you...
- English-speaking
- Capable of becoming pregnant (not permanently sterilized and not using a highly effective long-acting reversible birth control method such as intrauterine device or implant)
- Engaged in vaginal sex with a male partner during the three years prior to arrest or entering the treatment program
- Used at least one substance (heroin, fentanyl, opioids, cocaine, methamphetamine, or marijuana or alcohol with another substance) in the three months prior to arrest or entering the treatment program
- For women recruited from the MAT Program: expected length of incarceration at the St. Louis County Jail is 2 to 6 months with expected release into the community
You will not qualify if you...
- Participated in a focus group that helped create the intervention adaptation
- Non-English-speaking
- Not capable of becoming pregnant (permanently sterilized or using a long-acting reversible contraceptive method)
- No vaginal sex with a male partner in the three years prior to incarceration or entering the treatment program
- No use of an illicit substance or only alcohol or marijuana use not combined with another substance
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Trial Site Locations
Total: 1 location
1
Buzz Westfall Justice Center
St Louis, Missouri, United States, 63105
Actively Recruiting
Research Team
J
Jennifer R Bello Kottenstette, MD
CONTACT
P
Phebe Madhusudanan, MD, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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