Actively Recruiting

Age: 30Years - 85Years
FEMALE
NCT03448926

The PREDICT Registry:

Led by PreludeDx · Updated on 2026-04-17

3000

Participants Needed

30

Research Sites

978 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective, non-interventional (observational) cohort study conducted within the medical network of the participating investigators and institutions. Patients meeting the eligibility criteria (see below) will be eligible for participation and the investigators will obtain written informed consent. A central Institutional Review Board (IRB), WCG IRB, will approve the protocol and each participating institution.

CONDITIONS

Official Title

The PREDICT Registry:

Who Can Participate

Age: 30Years - 85Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically confirmed ductal carcinoma in situ (DCIS) in a single breast (presence of lobular carcinoma in situ or other benign breast disease allowed)
  • DCISionRT test ordered during routine patient care
  • Eligible for or recently completed breast conserving surgery
  • Eligible to receive radiation and/or systemic treatment
  • Between 30 and 85 years old
  • Tumor size less than 6 cm
  • Diagnosed with DCIS within 120 days of consent
Not Eligible

You will not qualify if you...

  • Insufficient tissue to generate DCISionRT test results or missing required inputs (age, tumor size, margin status, palpability)
  • Evidence of invasive breast cancer, including microinvasion, lymph node involvement, Paget's disease of the nipple, or suspicious lymph node or contralateral breast mammogram findings
  • Surgically treated with ipsilateral mastectomy for primary DCIS
  • Prior ipsilateral or contralateral breast DCIS or invasive breast cancer
  • Prior in-field radiation in the ipsilateral breast
  • Prior systemic endocrine or chemotherapy before testing
  • Pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 30 locations

1

Arizona Center for Cancer Care

Scottsdale, Arizona, United States, 85258

Actively Recruiting

2

University of California San Diego

La Jolla, California, United States, 92093

Actively Recruiting

3

Sutter Health

San Mateo, California, United States, 94401

Actively Recruiting

4

University of Colorado Anschutz Medical Campus

Aurora, Colorado, United States, 80045

Actively Recruiting

5

Baptist MD Anderson Cancer Center

Jacksonville, Florida, United States, 32207

Actively Recruiting

6

BayCare Health System

Tampa, Florida, United States, 33607

Actively Recruiting

7

University of South Florida

Tampa, Florida, United States, 33613

Actively Recruiting

8

Emory University Winship Cancer Institute

Atlanta, Georgia, United States, 30322

Actively Recruiting

9

Endeavor Health (Northshore)

Evanston, Illinois, United States, 60201

Actively Recruiting

10

MedStar Health Research Institute

Baltimore, Maryland, United States, 21237

Actively Recruiting

11

Dana-Farber Cancer Institute

Boston, Massachusetts, United States, 02115

Actively Recruiting

12

Corewell Health William Beaumont University Center

Royal Oak, Michigan, United States, 48073

Actively Recruiting

13

Comprehensive Breast Care

Troy, Michigan, United States, 48098

Actively Recruiting

14

Washington University School of Medicine

St Louis, Missouri, United States, 63110

Actively Recruiting

15

Maimonides Cancer Center

Brooklyn, New York, United States, 11220

Actively Recruiting

16

Northwell Health Center for Advanced Medicine

Lake Success, New York, United States, 11042

Actively Recruiting

17

NYU - Long Island

Mineola, New York, United States, 11501

Actively Recruiting

18

NYU - Manhattan

New York, New York, United States, 10016

Actively Recruiting

19

Columbia University Medical Center

New York, New York, United States, 10032

Actively Recruiting

20

Cleveland Clinic Akron General

Akron, Ohio, United States, 44302

Actively Recruiting

21

Cleveland Clinic Foundation-Taussig Cancer Inst

Cleveland, Ohio, United States, 44195

Actively Recruiting

22

The Ohio State University

Columbus, Ohio, United States, 43212

Actively Recruiting

23

Compass Oncology

Tigard, Oregon, United States, 97223

Actively Recruiting

24

St Luke's University Health Network

Easton, Pennsylvania, United States, 18045

Actively Recruiting

25

Sidney Kimmel Comprehensive Cancer Ctr - Jefferson

Philadelphia, Pennsylvania, United States, 19027

Actively Recruiting

26

AHN Allegheny General Hospital

Pittsburgh, Pennsylvania, United States, 15212

Actively Recruiting

27

Nashville Breast Center

Nashville, Tennessee, United States, 37203

Actively Recruiting

28

UT Southwestern Medical Center

Dallas, Texas, United States, 75235

Actively Recruiting

29

Baylor College of Medicine

Houston, Texas, United States, 77030

Actively Recruiting

30

Texas Oncology

Plano, Texas, United States, 75093

Actively Recruiting

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Research Team

S

Steven C Shivers, PhD

CONTACT

L

Leona Hamrick, DHSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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