Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT06681844

Predict Tooth Wear

Led by Hospices Civils de Lyon · Updated on 2024-11-08

1000

Participants Needed

5

Research Sites

207 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Tooth wear, resulting from gradual loss of dental hard tissue due to mechanical and chemical factors, impacts tooth structure, texture, and function. It affects quality of life, with varying prevalence (26.9% to 90.0%), and is traditionally detected visually during check-ups, often at advanced stages. Monitoring alterations in tooth shape via intraoral scanners aids early detection, but restoration remains challenging. Prevention through early detection is vital, as patients may not fully comprehend tooth structure loss until visible. Recently, statistical shape analysis (SSA) used to learn the tooth anatomy and define a reference shape (biogeneric tooth) using. However, assuring landmark consistency is challenging mostly due to biases of the operator. Recently, a robust method called MEG-IsoQuad offered automated, isotopological remeshing. Combining this with SSA holds promise for diagnostic and simulation purposes. This study aims to assess the reliability of a remeshing-SSA approach for altered and intact premolar analysis and compare machine learning algorithms for simulating the shape of the initially intact tooth or future altered one. The clinical perspective of the current work offers possibilities to: * Prevent future tooth wear by detecting it at an early stage; and communicate better to the patient by presenting him/her potential future altered teeth * Simulate the adapted reconstruction for the altered tooth by simulating the initially intact one

CONDITIONS

Official Title

Predict Tooth Wear

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Teeth avulsed with a tooth wear index between 0 and 3
  • Mature incisor, canine, premolar, or first and second molars
  • Participants aged 18 to 80 years
Not Eligible

You will not qualify if you...

  • Teeth avulsed with a tooth wear index over 3 or with oral rehabilitation representing similar wear
  • Immature teeth or teeth without fully developed roots
  • Wisdom teeth

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Indiana University Hospital

Indianapolis, Indiana, United States, 46202

Actively Recruiting

2

KU Leuven University Hospital

Leuven, Belgium

Actively Recruiting

3

Lyon Dental Hospital

Lyon, France, 69007

Actively Recruiting

4

King George Medical University

Lucknow, India

Actively Recruiting

5

Tel Aviv Universi

Tel Aviv, Israel

Actively Recruiting

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Research Team

R

Raphael Richet, Clinical Assistant

CONTACT

M

Maxime Ducret, Professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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