Actively Recruiting
Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease
Led by University Hospital, Bonn · Updated on 2022-05-18
200
Participants Needed
1
Research Sites
327 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Prospective, observational study to define precipitants and predictors of development of Acute-on-Chronic Liver Failure (ACLF) after surgical interventions, allowing to develop a risk stratification for elective procedures in cirrhotic patients. As well as identifying molecular mechanisms of post-interventional ACLF and thus preparing the ground for development of new therapeutic approaches.
CONDITIONS
Official Title
Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female adult (≥18 years) patient
- With or without liver cirrhosis diagnosed by histology or clinical, laboratory, and radiological signs
- Or with non-cirrhotic portal hypertension
- Non-pregnant, non-lactating females
- Ability to understand study information and provide written informed consent
- Cooperative and available for the entire study
- Indication for surgical intervention
You will not qualify if you...
- Pregnant or lactating females
- Patients having surgery for palliative cancer treatment
- Patients with severe extra-hepatic diseases
- HIV-positive patients
- Patients with previous liver or other organ transplant
- Patients with acute or subacute liver failure without cirrhosis
- Patients who decline participation
- Physician's denial due to inability to follow protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital Bonn
Bonn, Germany
Actively Recruiting
Research Team
M
Michael Praktiknjo, MD
CONTACT
J
Johannes Chang, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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