Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT06408116

Predicting Esophageal Cancer Borders Using PET-Imaging

Led by University Hospital Heidelberg · Updated on 2026-03-10

30

Participants Needed

1

Research Sites

213 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study examines the diagnostic precision of endosonography, mpMRI and PET/CT in defining tumor boundaries and tumor spread before and after neoadjuvant therapy and definitive surgery.

CONDITIONS

Official Title

Predicting Esophageal Cancer Borders Using PET-Imaging

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically confirmed adenocarcinoma or squamous cell carcinoma of the esophagus, including AEG I and AEG II tumors in the primary situation
  • Planned surgical treatment of esophageal carcinoma
  • Possible staging advantage through FAPI PET/CT diagnostics
  • Patient information and written consent
  • KI 60% or ECOG 0/1 (at least: self-sufficiency)
  • Age �318 years
Not Eligible

You will not qualify if you...

  • Previous radiation therapy in the tumor region
  • Previous tumor disease with less than 5 years of remission
  • Surgical therapy is not functionally or technically possible
  • Distant metastasis
  • Patient is not capable of giving consent
  • Concurrent participation in another clinical trial that could affect the results of this trial or the other trial
  • Illnesses that do not allow the person concerned to assess the nature and scope as well as possible consequences of the clinical study
  • Pregnant or breastfeeding women
  • Signs that the person taking part is unlikely to comply with the therapy (e.g. unwillingness to cooperate)

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Department of Radiotherapy, University of Heidelberg

Heidelberg, Germany, 69120

Actively Recruiting

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Research Team

C

Christoph Fink, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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