Study to Predict Language Recovery After Stroke Using Core Language Processing Assessment and Brain Imaging

What this Trial Is About

Stroke affects many people and often leads to lasting difficulties with movement and thinking. One serious problem is aphasia, which affects language skills and can be hard to recover from if not treated early. Researchers are studying whether tests done soon after a stroke, including a language test called the Core Assessment of Language Processing CALAP, can predict how well patients will recover their language abilities later on. This study includes patients hospitalized within 21 days of a stroke affecting one side of the brain. Participants will undergo language and cognitive assessments, brain MRI scans, and neurological exams during their hospital stay and again between 3 and 18 months later. Researchers will use these data to build models predicting language and cognitive recovery and to see if early language tests combined with MRI and neuropsychological data improve prediction. They will also examine if language rehabilitation changes these predictions. Participants will be involved in two main visits for assessments including clinical exams, cognitive tests, and MRI scans. The study aims to follow about 570 stroke patients over 6 years. The main measure is how well the CALAP score predicts language recovery 18 months after stroke. Secondary measures include improving predictions using MRI, neuropsychological data, and rehab information. This research hopes to help guide better care and rehabilitation for stroke survivors with language difficulties.

Predicting Language Recovery in Acute Stroke Patients in the Neurovascular Intensive Care Unit: An Exploratory Study With the Core Assessment of Language Processing.