Imaging-Based Diagnostic Model for Kidney Cancer Tumor Thrombus Invasion of the Inferior Vena Cava Wall Based on Evidence from Pathological Examination

What this Trial Is About

This research aims to create a preoperative imaging diagnostic model that closely matches the results of histopathological examinations for patients with renal cell carcinoma RCC that has tumor thrombus invading the inferior vena cava IVC vascular wall. The study also seeks to develop an accurate and systematic pathological grading standard for IVC vascular wall invasion. It will explore how different layers of vascular wall invasion affect long-term prognosis and clinical treatment decisions in RCC with IVC tumor thrombus. The study includes patients diagnosed with primary RCC with IVC tumor thrombus who undergo radical nephrectomy and at least one form of IVC thrombectomy. Participants are divided into two groups based on pathological examination results those with IVC vascular wall invasion invaded group and those without non-invaded group. The study will analyze imaging tests such as abdominal ultrasound, contrast-enhanced ultrasonography, CT, and MRI to identify features of vascular wall invasion and establish a reliable preoperative diagnostic model aligned with pathological findings. Participants will be followed for three years to assess outcomes including local and distant recurrence, overall survival, and recurrence-free survival. Researchers will collect data from preoperative imaging, surgical details, pathological specimens, and postoperative recovery. Multiple clinical and imaging assessments will be conducted before surgery, with long-term monitoring of tumor metastasis and patient health status. This comprehensive follow-up aims to inform better preoperative treatment strategies and surgical planning for RCC patients with IVC tumor thrombus.

Predicting Model Based on Evidence-based Pathological Diagnose Criteria for RCC Tumor Thrombus With IVC Wall Invasion