Actively Recruiting

Age: 18Years +
FEMALE
NCT05942313

Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

Led by Ilana Hull · Updated on 2026-03-19

100

Participants Needed

1

Research Sites

170 weeks

Total Duration

On this page

Sponsors

I

Ilana Hull

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study will be a 12-month prospective, genotype-blinded longitudinal observational study with current standard of clinical care. This study will enroll 100 pregnant women with OUD at UPMC Hospitals with its high volumes. Because of the observational nature of the study, the anticipated dropout rate will be ≤ 20%. Investigators expect the effective sample size of evaluable patients will be 200 with longitudinal data.

CONDITIONS

Official Title

Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant women with opioid use disorder (OUD) and their infant
  • Currently on buprenorphine or methadone treatment for OUD
  • Enrolled in a prenatal opioid maintenance program
  • Age greater than 18 years
  • Singleton pregnancy
  • Planned delivery at UPMC's Magee Womans Hospital
  • Positive opioid urine screen results
Not Eligible

You will not qualify if you...

  • Serious maternal medical illness making study participation difficult
  • HIV or AIDS infection
  • Known major fetal congenital abnormalities

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UPMC Magee-Womens Hospital

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

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Research Team

A

Amy Monroe, MPH, MBA

CONTACT

C

Carly Riedmann, MPH

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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