Actively Recruiting

Age: 30Years +
All Genders
Healthy Volunteers
NCT03689595

Predicting Progression of Developing Myeloma in a High-Risk Screened Population (PROMISE)

Led by Dana-Farber Cancer Institute · Updated on 2026-05-07

30000

Participants Needed

1

Research Sites

782 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The PROMISE Study aims to establish a prospective cohort of individuals with precursor conditions to multiple myeloma, such as monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). We will study these patients as a means to identify risk factors for progression to symptomatic multiple myeloma.

CONDITIONS

Official Title

Predicting Progression of Developing Myeloma in a High-Risk Screened Population (PROMISE)

Who Can Participate

Age: 30Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 30 years or older
  • Self-identified African American race and/or first-degree relative of a patient with a plasma cell disorder such as MGUS, SMM, multiple myeloma, or Waldenström's Macroglobulinemia, or another blood cancer
  • Individuals over 18 years old with two or more family members diagnosed with a blood cancer
Not Eligible

You will not qualify if you...

  • Persons diagnosed with any cancer requiring active treatment
  • Persons already diagnosed with plasma cell disorders such as MGUS, SMM, multiple myeloma, or Waldenström's Macroglobulinemia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Dana Farber Cancer Institute

Boston, Massachusetts, United States, 02215

Actively Recruiting

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Research Team

I

Irene Ghobrial, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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