Actively Recruiting
Predicting Progression of Developing Myeloma in a High-Risk Screened Population and General Population
Led by Tel-Aviv Sourasky Medical Center · Updated on 2026-02-04
2000
Participants Needed
3
Research Sites
247 weeks
Total Duration
On this page
Sponsors
T
Tel-Aviv Sourasky Medical Center
Lead Sponsor
D
Dana-Farber Cancer Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
We will seek consent from participants to use the data and biospecimens collected according study protocol to address additional research questions for MGUS, SMM, MM, and other conditions. Our overarching hypothesis is that early detection of MGUS/SMM in a high- risk population, along with the comprehensive characterization of genomic/epigenomic and microenvironmental/immune regulators of disease progression will lead to strategies that intercept disease progression and improve survival.
CONDITIONS
Official Title
Predicting Progression of Developing Myeloma in a High-Risk Screened Population and General Population
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be at least 30 years old and have a first-degree relative diagnosed with a plasma cell disorder such as MGUS, SMM, MM, Waldenstrtrms Macroglobulinemia, or another blood cancer
- OR be 18 years or older with two or more first- or second-degree relatives diagnosed with a plasma cell disorder or another blood cancer
- Provide voluntary written informed consent with understanding that consent can be withdrawn at any time without affecting future medical care
You will not qualify if you...
- Have a diagnosis of cancer at any site, including blood cancers, requiring active treatment
- Have a previously diagnosed plasma cell disorder such as MGUS, SMM, MM, or Waldenstrtrms Macroglobulinemia
- Be a female with a positive serum pregnancy test during screening or a positive pregnancy test
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Soroka
Beersheba, Israel
Actively Recruiting
2
Rabin medical center
Petah Tikva, Israel
Actively Recruiting
3
TASMC
Tel Aviv, Israel
Actively Recruiting
Research Team
I
Irit Avivi, Prof
CONTACT
E
Ella Krayzler
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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