Actively Recruiting
Predicting Psychotic Relapse Using Speech-Based Early Detection
Led by Douglas Mental Health University Institute · Updated on 2025-05-18
250
Participants Needed
3
Research Sites
265 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Psychotic disorders, including schizophrenia and affective psychosis, are severe mental health conditions marked by recurrent episodes that contribute to long-term disability. Relapses, characterized by the re-emergence of psychotic symptoms after remission, are a critical factor in the progression of these disorders, increasing risks such as suicide, cognitive impairment, and unemployment. This study aims to develop a novel, speech-based digital model to predict relapses in individuals with psychosis. Building on previous research into language abnormalities in schizophrenia, the study will employ a longitudinal design across Early Psychosis Intervention (EPI) clinics in Ontario and Quebec to advance relapse prediction
CONDITIONS
Official Title
Predicting Psychotic Relapse Using Speech-Based Early Detection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age must be 16 years and older
- Diagnosis must meet DSM-5 criteria for psychotic disorders, including schizophrenia, schizoaffective disorder, or related conditions
- Fluency in English or French
- Must be currently receiving treatment through an Early Psychosis Intervention (EPI) program
You will not qualify if you...
- Severe comorbid speech or language disorders such as aphasia
- Primary diagnosis of non-psychotic disorders
- Inability to provide consent or complete assessments
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Robarts Research Institute
London, Ontario, Canada, N6A 5B7
Actively Recruiting
2
Douglas Mental Health University Institute
Montreal, Quebec, Canada, H4H 1A8
Actively Recruiting
3
Vitam
Québec, Quebec, Canada, G1J 2G1
Actively Recruiting
Research Team
L
Lena Palaniyappan, MD, PHD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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