Actively Recruiting
Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat
Led by State University of New York at Buffalo · Updated on 2026-01-26
24
Participants Needed
1
Research Sites
121 weeks
Total Duration
On this page
Sponsors
S
State University of New York at Buffalo
Lead Sponsor
U
United States Department of Defense
Collaborating Sponsor
AI-Summary
What this Trial Is About
The overall goal of this project is to identify a work/rest cycle that allows for faster mission completion needed in emergency situations, compared to current Army heat guidance, while mitigating heat strain and neuromuscular fatigue. This project will determine the trade-off between faster mission completion and risk of heat strain and physical performance decrements. Completion of this project will allow military leaders to make informed decisions by understanding the impact of their choices on the magnitude of physical performance decrements and expected heat casualties, setting up hot weather missions for success.
CONDITIONS
Official Title
Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy individuals
- Physically active
You will not qualify if you...
- History of cardiovascular, metabolic (such as clinical thyroid disease), respiratory, neural, or renal disease
- Hypertensive (systolic blood pressure > 139 mmHg, diastolic blood pressure > 89 mmHg) or tachycardic (heart rate > 100 bpm) during the screening visit
- Taking medications or supplements known to affect physiologic responses to exercise or thermoregulation (e.g., beta blockers, omega-3 fatty acids, statins, aspirin)
- Tobacco or nicotine use currently or in the past six months
- Musculoskeletal injury expected to impact exercise in the protocol
- A positive pregnancy test at any point in the study
- Study physician discretion based on any other medical condition or medication
- Inability to understand or follow instructions or the protocol
- Gastrointestinal disease or previous surgery prohibiting core temperature capsule use. Participants with a contraindication can opt to insert the pill rectally as a suppository.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Center for Research and Education in Special Environments
Buffalo, New York, United States, 14214
Actively Recruiting
Research Team
R
Riana R Pryor, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
4
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