Actively Recruiting

Age: 70Years - 99Years
All Genders
NCT06344208

Predicting Toxicity in Elderly Patients With Head and Neck Cancer

Led by European Institute of Oncology · Updated on 2026-03-24

3

Participants Needed

1

Research Sites

250 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Predicting toxicity in elderly patients with head and neck cancer: validating a disease-oriented toxicity predictive tool and integrating it with avail-able screening tools for better outcomes.

CONDITIONS

Official Title

Predicting Toxicity in Elderly Patients With Head and Neck Cancer

Who Can Participate

Age: 70Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 70 years or older
  • Histological diagnosis of squamous cell or undifferentiated head and neck cancer in stage III-IV AJCC edition VIII (including sinonasal, nasopharynx, oral cavity, oropharynx, unknown primary with HPV positive, larynx, and hypopharynx)
  • Planned for curative non-surgical treatment (radiotherapy alone, chemoradiation with platinum salts, or radiation plus cetuximab)
  • Disease evaluable according to RECIST criteria 1.1
  • Willing to sign written informed consent
  • Adequate organ function
Not Eligible

You will not qualify if you...

  • Cancer in other sites than head and neck within the past 2 years, except for prostate cancer cT1-2 Gleason 3+3, non-invasive melanoma, initial non-melanoma skin cancer, or in situ cervical cancer
  • ECOG performance status 3 or 4
  • Previous systemic treatments for other primary tumors

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
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Trial Site Locations

Total: 1 location

1

European Institute of Oncology

Milan, Milan, Italy, 20141

Actively Recruiting

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Research Team

M

Maria Cossu Rocca, MD

CONTACT

F

francesca lombardi

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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