Actively Recruiting
Prediction of Anxiety and Memory State
Led by Columbia University · Updated on 2026-01-28
40
Participants Needed
1
Research Sites
123 weeks
Total Duration
On this page
Sponsors
C
Columbia University
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to look at how signals in the brain, body, and behavior relate to anxiety and memory function. This project seeks to develop the CAMERA (Context-Aware Multimodal Ecological Research and Assessment) platform, a state-of-the-art open multimodal hardware/software system for measuring human brain-behavior relationships. The R61 portion of the project is designed to develop the CAMERA platform, which will use multimodal, passive sensor data to predict anxiety-memory state in patients undergoing inpatient monitoring with intracranial electrodes for clinical epilepsy, as well as to build CAMERA's passive data framework and active data framework.
CONDITIONS
Official Title
Prediction of Anxiety and Memory State
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients must have known or suspected Temporal Lobe Epilepsy.
- Native or proficient in speaking English or Spanish.
- Stereoelectroencephalography (sEEG) cases: The implant plan must include hippocampal head, body, and tail electrodes either unilaterally or bilaterally.
- 7th grade reading level (minimum level considered literate for adults)
You will not qualify if you...
- Hearing impaired (not corrected with a hearing aid)
- Unable to read the newspaper at arm's length with corrective lenses.
- Objective intellectual impairment (estimated IQ less than 70)
- Any history of Electroconvulsive Therapy or psychosis (except postictal psychosis for patients)
- Lifetime psychotic disorder
- Current Anxiety disorder, Major Depressive Disorder, or Bipolar Disorder
- Neurodegenerative diseases, widespread brain lesions, language problems (other than naming difficulty)
- Medical conditions that could affect cognitive performance (e.g., HIV infection, metastatic cancer)
- Acute renal failure or end-stage renal disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Columbia University Irving Medical Center
New York, New York, United States, 10032
Actively Recruiting
Research Team
B
Brett E Youngerman, MD
CONTACT
A
Angela Velazquez
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SCREENING
Number of Arms
1
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