Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05375370

Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment by Monitoring Circulating Tumor DNA

Led by University Hospital, Rouen · Updated on 2026-02-06

150

Participants Needed

1

Research Sites

339 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of the REMNANT study is to confirm the clinical value of detecting a new biomarker, ctDNA (circulating tumor DNA), in the follow-up of patients with operated liver cancer. In order to meet this objective, this biomarker will be measured in your blood before and after surgery, at three and six months.

CONDITIONS

Official Title

Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment by Monitoring Circulating Tumor DNA

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age �3e= 18 years
  • Hepatocellular carcinoma diagnosed by consensus radiological criteria in cirrhotic patients or histologically if imaging diagnosis is not available
  • Patient treated by liver resection surgery or radiofrequency tumor destruction
  • Treatment decision confirmed by digestive oncology multidisciplinary team
  • Patient has read and understood study information and signed consent
  • Patient will be followed up at Charles Nicolle University Hospital in Rouen
Not Eligible

You will not qualify if you...

  • Presence of other active cancer or blood malignancy
  • Contraindication to surgery
  • Not affiliated to the social security system
  • Pregnant, recently gave birth, or breastfeeding
  • Under court protection, guardianship, or curatorship

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Chu Rouen

Rouen, France, 76031

Actively Recruiting

Loading map...

Research Team

E

Edouard ROUSSEL, MD

CONTACT

J

Julie RONDEAUX

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here