Actively Recruiting
Prediction of Neoadjuvant Chemotherapy Efficacy in Locally Advanced Gastric Cancer
Led by Ruijin Hospital · Updated on 2024-01-09
40
Participants Needed
1
Research Sites
365 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study intends to explore the value of 68Ga-FAPI-04 and 18F-FDG PET/CT in the evaluation of treatment response to neoadjuvant chemotherapy(NAC) for patients with locally advanced gastric cancer(LAGC).
CONDITIONS
Official Title
Prediction of Neoadjuvant Chemotherapy Efficacy in Locally Advanced Gastric Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18-75 years.
- Histologically confirmed gastric adenocarcinoma through gastroscopy.
- Resectable gastric cancer.
- ECOG performance status 0-1.
- White blood count >4x10^9/L, Absolute neutrophil count (ANC) >2x10^9/L, Hemoglobin (Hb) >90g/L, Platelets >100x10^9/L.
- Ejection fraction >50%.
- Serum bilirubin <1.5 times upper limit of normal (ULN); ALT and AST <1.5 times ULN.
- Serum creatinine ≤1.5 times ULN, or glomerular filtration rate (GFR) >60 ml/min.
- Agreement to participate in this study with informed consent form.
- Willingness and ability to comply with the protocol for the duration of the study.
- No children bearing potential in the next six months before enrollment.
You will not qualify if you...
- Having second primary malignant diseases in past five years, except cured basal cell and squamous cell carcinoma of the skin.
- Known hypersensitivity reaction to chemotherapy drugs or contraindications to chemotherapy.
- Severe disease or other unsuitable conditions as determined by investigators, including inadequate organ function.
- Uncontrollable diabetes or fasting blood glucose level ≥11 mmol/L on test day.
- Severe mental symptoms, unconsciousness, or inability to complete the examination.
- Pregnancy, possible pregnancy, or breastfeeding.
- Lack of compliance with study requirements.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Shanghai Ruijin Hospital
Shanghai, Shanghai Municipality, China, 200025
Actively Recruiting
Research Team
Y
Ying Miao
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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