Actively Recruiting
Prediction of Post-stroke Motor Recovery
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2024-02-05
200
Participants Needed
1
Research Sites
336 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The prediction of motor recovery in the acute phase of stroke is crucial for several clinical reasons: (i) informing the patient and his relatives, (ii) helping to identify the patient's endorsement (return home or rehabilitation) as well as the adaptation of the rehabilitation program to what can be expected from it. To date, an algorithm (decision tree) proposed by C. Stinear's team named PREP2 is the best predictive tool with 75% of patients well classified at 3 months. It predicts the functional recovery of the upper limb after stroke 3 months before the episode by categorizing recovery as "excellent", "good", "limited" as well as "minor" (poor). With two data (SAFE score, age) or three (SAFE score, Motor evoked potential, NIHSS), the prediction is effective three times out of 4. In the study the team is proposing "PREP-UCV", it would like to validate this algorithm as it is with patients in the active file who are victims of stroke. The expected accuracy is 75% or more. As a secondary objective, the team would like to confirm that it find the same algorithm starting from the initial data from PREP 2 (side of the stroke, type of stroke (ischemic and / or hemorrhagic), involvement of the corticospinal tract on MRI, sex at birth ) as well as two other factors which are also very important: cognitive status (dysexecutive / aphasia / neglect), as well as the neutrophils on lymphocytes ratio.
CONDITIONS
Official Title
Prediction of Post-stroke Motor Recovery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Admitted in the Pitié-Salpêtrière stroke unit
- Stroke with an upper limb motor deficit
- Agree to participate
You will not qualify if you...
- Contraindication to MRI or transcranial magnetic stimulation (TMS)
- Under legal guardianship
- No healthcare insurance
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Service des Urgences Cérébro-Vasculaires, Hôpital Pitié Salpêtrière
Paris, France, 75013
Actively Recruiting
Research Team
C
Charlotte ROSSO, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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