Evaluating Inflammation Markers to Predict Postdural Puncture Headache in Pregnant Women After Cesarean Section with Spinal Anesthesia

What this Trial Is About

This research aims to evaluate how well inflammation index values, calculated from routine blood tests before and after surgery, can predict postdural puncture headache PPH in pregnant women undergoing cesarean section with spinal anesthesia. PPH is a common complication after spinal anesthesia characterized by headaches that worsen when upright and ease when lying down, often accompanied by symptoms like nausea and neck pain. The study also investigates how factors like age, weight, previous headache history, and other patient data relate to PPH development. Participants are pregnant women aged 18 to 45 undergoing elective cesarean section under spinal anesthesia. Researchers will use blood samples taken before and after surgery to calculate several inflammatory marker values. The study observes two groups those who develop PPH after the cesarean and those who do not. These markers include the pan-immune inflammation value, systemic immune-inflammation index, and systemic inflammatory response index, which are derived from blood cell counts. During the study, participant data such as demographic details, blood group, infant birth weight, and smoking status will be collected from medical records. Researchers will monitor for PPH symptoms over 5 days post-surgery. The main outcome is assessing how well inflammation indices predict PPH within this period, along with determining PPH frequency and related symptoms. The study is observational, with no treatments administered, and participation involves standard clinical care and blood testing during the cesarean process.

Prediction of Postdural Puncture Headache