Actively Recruiting
Prediction of Propofol Effect-Site Concentration Associated With Deep Anesthesia
Led by Ciusss de L'Est de l'Île de Montréal · Updated on 2026-01-16
110
Participants Needed
1
Research Sites
90 weeks
Total Duration
On this page
Sponsors
C
Ciusss de L'Est de l'Île de Montréal
Lead Sponsor
C
Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this observational study is to explore the variability of the concentration at the effect site (Ce) of propofol to reach deep anesthesia (DA) during induction of general anesthesia in adults. The investigators hypothesized that there is a great variability in this Ce that could be precisely explained by * Electroencephalographic (EEG) features available prior to induction of anesthesia * Cognitive performance * Patients characteristics Participants will undergo preoperative cognitive testing and awake EEG. Then, induction of general anesthesia will be performed using continuous infusion of propofol. The Ce at which Deep anesthesia is observed will be recorded.
CONDITIONS
Official Title
Prediction of Propofol Effect-Site Concentration Associated With Deep Anesthesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled for any kind of surgery under general anesthesia.
- Adults
You will not qualify if you...
- Inability to communicate in French or English
- Known allergy or intolerance or other medical condition that precludes the use of prescribed general anesthesia protocol for this study
- Patients requiring rapid sequence induction
- Anticipated or known difficult intubation patient
- Anticipated or known difficult ventilation patient
- Body mass index 60; 35 kg.m-2
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hopital Maisonneuve-Rosemont
Montreal, Quebec, Canada, H1T 2M4
Actively Recruiting
Research Team
L
Louis Morisson, MD, MSc
CONTACT
N
Nadia Godin, RN
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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