Actively Recruiting

Age: 18Years +
All Genders
NCT06466811

Prediction of Undesired Obstruction in External Ventricular Drains.

Led by Nantes University Hospital · Updated on 2024-07-12

640

Participants Needed

1

Research Sites

125 weeks

Total Duration

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AI-Summary

What this Trial Is About

Acute obstructive hydrocephalus often complicates intraventricular hemorrhage (IVH). The insertion of an external ventricular drain (EVD) is typically necessary in order to alleviate intracranial pressure by draining excess fluid. However, dysfunction of the EVD whether due to malposition or obstruction, can exacerbate hydrocephalus in an already compromised brain. EVD dysfunction must therefore be promptly detected and treated. Consequently, identifying high-risk patients and closely monitoring them is imperative. While IVH is known to increase the risk of obstruction in the natural cerebrospinal fluid outflow tract, its association with ventricular drain obstruction remains unproven.

CONDITIONS

Official Title

Prediction of Undesired Obstruction in External Ventricular Drains.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

Inclusion Criteria :

Patient older than 18 years old,

  • admitted to the ICU,
  • with first EVD inserted for less than 12 hours,
  • and brain imaging (CT or MRI) available in the timespan "24 hours before to 24 hours after" the EVD insertion.

Exclusion Criteria :

  • EVD intentionally occluded immediately after its insertion,
  • purulent cerebrospinal fluid
  • Pregnant or breast-feeding patient
  • Moribund patient or patient with decision of withholding or withdrawing life-sustaining treatment within the 12 hours
  • Patient with no health insurance
  • Patient under guardianship
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Nantes University Hospital

Nantes, Loire-Atlantique, France, 44093

Actively Recruiting

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Research Team

K

Karim LAKHAL, PH

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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