Actively Recruiting

Age: 65Years +
All Genders
NCT07412379

Predictive Factors for Functional and Quality of Life Decline in Patients >65 Years With a Gastrointestinal Tract Cancer Diagnosis Taken to Curative Resectable Surgery

Led by Hospital Universitario Mayor Méderi · Updated on 2026-02-17

327

Participants Needed

1

Research Sites

204 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Introduction: Human life expectancy has increased significantly, leading to a transformation in the global demographic structure. Cancer is considerably more common among older adults compared to younger populations, as age is one of the main risk factors for its development. In fact, most solid tumors are considered age-related diseases. For this reason, the incidence of cancer among older individuals is expected to continue rising. Oncological care for this population group is particularly complex and represents a significant challenge, as comorbidities and the social aspects of aging create clinical scenarios that differ greatly from those seen in younger patients. Objective: To identify the predictive factors of functional decline and quality of life at 12 months of follow-up, as well as oncological outcomes at 5 years of follow-up, in patients aged 65 years and older with gastrointestinal cancer who undergo curative-intent resective surgery at Hospital Universitario Mayor - Méderi, Bogotá, Colombia. Methodology: Longitudinal and analytical observational study of prospective prognostic cohort type. Expected Results: Predictive model of functional decline and quality of life, as well as oncological outcomes, in patients with gastrointestinal cancer undergoing curative-intent surgical procedures.

CONDITIONS

Official Title

Predictive Factors for Functional and Quality of Life Decline in Patients >65 Years With a Gastrointestinal Tract Cancer Diagnosis Taken to Curative Resectable Surgery

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of gastrointestinal tract cancer (including esophagus, stomach, duodenum, pancreas, liver, biliary tract, small bowel, appendix, colon, or rectum)
  • Disease must be resectable by surgery
  • Surgery planned with curative intent
  • Willingness to participate and provide informed consent
  • Receiving care within the Mederi Hospital Network
Not Eligible

You will not qualify if you...

  • Death prior to surgery
  • Lost to follow-up during the study
  • Not undergoing surgery
  • Emergency surgery cases
  • Surgery due to cancer relapse or complications from a previous procedure
  • Treatment by endoscopy only
  • Diagnosis of a second primary tumor without at least 5 years disease-free from the first tumor
  • Baseline functional status of 0/6 on the Katz score

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Hospital Universitario Mayor-Méderi

Bogotá, Colombia

Actively Recruiting

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Research Team

C

Camilo Ramírez-Giraldo, Surgeon

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Predictive Factors for Functional and Quality of Life Decline in Patients >65 Years With a Gastrointestinal Tract Cancer Diagnosis Taken to Curative Resectable Surgery | DecenTrialz