Risk Factors for Pancreatic Fistula After Pancreaticoduodenectomy Surgery in Patients with Pancreas and Periampullary Tumors

What this Trial Is About

This research investigates the predictive risk factors for clinically relevant postoperative pancreatic fistula CR-POPF in patients undergoing pancreaticoduodenectomy PD, a complex surgery for malignant or benign tumors of the pancreatic head and periampullary region. The study highlights the high morbidity and mortality rates associated with PD and focuses on improving the prediction of POPF to enhance patient outcomes. It aims to identify risk factors during preoperative, intraoperative, and postoperative periods in 100 patients treated between 2025 and 2026. Participants undergo the pancreaticoduodenectomy procedure, which involves surgical removal of the pancreatic head and surrounding areas. The study follows patients who have undergone this operation to monitor the development of clinically relevant pancreatic fistula. There is a single study group consisting of patients who develop this complication. The study collects data across different periods to assess factors influencing the risk of POPF. During the study, participants are evaluated for the incidence of clinically relevant postoperative pancreatic fistula within 10 days after surgery. Researchers will collect clinical data before, during, and after the operation to identify risk factors. Participants must provide informed consent and agree to complete the study. The study monitors patient outcomes closely to help improve future treatment decisions and reduce mortality related to complications from PD.

Predictive Risk Factors for Pancreatic Fistula After Pancreaticoduodenectomy