Development and Validation of a Predictive Score for the Ischemic Cause of Transient Diplopia

What this Trial Is About

Researchers are studying transient diplopia, which is a brief episode of double vision, to understand its causes. This study focuses on distinguishing whether the diplopia is due to ischemic causes, which require urgent care, or other origins such as ophthalmological or non-ischemic neurological reasons. The goal is to develop a clinical score that helps doctors identify an ischemic cause quickly and accurately. Participants will undergo clinical, ophthalmological, and neurological evaluations. These include questionnaires about symptoms and vascular risk factors, brain imaging such as MRI and MRI angiography, heart monitoring with ECG and Holter, echocardiography, and various blood tests. Eye exams include visual field tests, optical coherence tomography, and retinography. The study observes adults who have experienced transient diplopia within the last 8 days. During the study, participants will be followed for 3 months to monitor the cause of their initial diplopia and any new ischemic events, including transient diplopia attacks, ischemic strokes, or transient ischemic attacks affecting vision or other functions. The main outcome is identifying whether the diplopia had an ischemic cause. Safety and ongoing health are monitored through these assessments over the follow-up period.

A Predictive Score for the Ischemic Etiology of a Transient Diplopia (VASCO-DIP)