Actively Recruiting

Age: 18Years +
All Genders
ID05098769

A Predictive Tool for Predicting Adverse Outcomes in Acute Pulmonary Embolism Patients Using Parameters Obtained by Computed Tomographic Pulmonary Angiography.

Led by Shengjing Hospital · Updated on 2026-03-11

300

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying acute pulmonary embolism, a condition where blood clots block lung arteries, to predict possible serious outcomes within 30 days after hospital admission. This observational study collects clinical, laboratory, and CT scan data from patients diagnosed with acute pulmonary embolism. The goal is to develop a predictive tool using these data to identify patients at higher risk of adverse events. Patients diagnosed with pulmonary embolism by CT pulmonary angiography and aged 18 or older are included. Participants are divided into two groups: one to create and assess a prediction model using logistic regression, and the other to validate this model. The model's accuracy is compared to existing risk assessment systems, aiming to improve early identification of patients who may experience complications. During the study, clinical and imaging data, including CT scans and laboratory tests like cardiac troponin I and NT-pro BNP levels, are collected from admission. Researchers monitor outcomes over 7 and 30 days to evaluate the occurrence of adverse events. The study tracks participants' health status to assess the prediction tool's performance and safety throughout the monitoring period.

CONDITIONS

Brief Title

A Predictive Tool for Predicting Adverse Outcomes in Acute Pulmonary Embolism Patients Using CTPA.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age of 18 years or older
  • Diagnosis of pulmonary embolism based on CT pulmonary angiography
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Received reperfusion treatment before hospital admission
  • Missing data on CT parameters, echocardiography, cardiac troponin I, or NT-pro BNP levels

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Admission day and shortly thereafter

Participants undergo computed tomographic pulmonary angiography (CTPA) and clinical assessments to collect parameters for predicting adverse outcomes.

1 visit (in-person)

Long-term Monitoring

Duration - 30 days

Participants are observed for adverse outcomes within 30 days after hospital admission.

Follow-up assessments during hospital stay and up to 30 days after admission

Trial Site Locations

Total: 1 location

1

Shenjing Hospital of CHINA MEDICAL UNIVERSITY

Shenyang, Liaoning, China

Actively Recruiting

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Research Team

Y

YIZHUO GAO

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Published Research Related To This Trial

Ventricular septum curvature ratio: a novel imaging marker to predict clinical deterioration in normotensive acute pulmonary embolism.

Yizhuo Gao, Zhichun Gu, Xuejiao Wei...

https://pubmed.ncbi.nlm.nih.gov/41174707

Predicting Deterioration in Patients With Normotensive Acute Pulmonary Embolism Using Clinical-Imaging Features: A Multicenter Prospective Cohort Study.

Yizhuo Gao, Shibo Wei, Yuchen Liu...

https://pubmed.ncbi.nlm.nih.gov/40576035