Ventricular septum curvature ratio: a novel imaging marker to predict clinical deterioration in normotensive acute pulmonary embolism.
Yizhuo Gao, Zhichun Gu, Xuejiao Wei...
https://pubmed.ncbi.nlm.nih.gov/41174707Actively Recruiting
Led by Shengjing Hospital · Updated on 2026-03-11
300
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are studying acute pulmonary embolism, a condition where blood clots block lung arteries, to predict possible serious outcomes within 30 days after hospital admission. This observational study collects clinical, laboratory, and CT scan data from patients diagnosed with acute pulmonary embolism. The goal is to develop a predictive tool using these data to identify patients at higher risk of adverse events. Patients diagnosed with pulmonary embolism by CT pulmonary angiography and aged 18 or older are included. Participants are divided into two groups: one to create and assess a prediction model using logistic regression, and the other to validate this model. The model's accuracy is compared to existing risk assessment systems, aiming to improve early identification of patients who may experience complications. During the study, clinical and imaging data, including CT scans and laboratory tests like cardiac troponin I and NT-pro BNP levels, are collected from admission. Researchers monitor outcomes over 7 and 30 days to evaluate the occurrence of adverse events. The study tracks participants' health status to assess the prediction tool's performance and safety throughout the monitoring period.
CONDITIONS
A Predictive Tool for Predicting Adverse Outcomes in Acute Pulmonary Embolism Patients Using CTPA.
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Admission day and shortly thereafter
Participants undergo computed tomographic pulmonary angiography (CTPA) and clinical assessments to collect parameters for predicting adverse outcomes.
1 visit (in-person)
Duration - 30 days
Participants are observed for adverse outcomes within 30 days after hospital admission.
Follow-up assessments during hospital stay and up to 30 days after admission
Total: 1 location
1
Shenjing Hospital of CHINA MEDICAL UNIVERSITY
Shenyang, Liaoning, China
Actively Recruiting
Y
YIZHUO GAO
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Yizhuo Gao, Zhichun Gu, Xuejiao Wei...
https://pubmed.ncbi.nlm.nih.gov/41174707Yizhuo Gao, Shibo Wei, Yuchen Liu...
https://pubmed.ncbi.nlm.nih.gov/40576035