The Predictive Value of Carotid Corrected Flow Time and Peak Flow Velocity Variability for Intradialytic Hypotension A Prospective Multicenter Observational Study

What this Trial Is About

Researchers are conducting a multicenter, prospective observational study to evaluate whether measurements from carotid ultrasonography can predict hypotension during maintenance hemodialysis. The study focuses on adult patients aged 18 to 80 with end-stage renal disease (ESRD) who have been on long-term hemodialysis for at least three months. The goal is to develop a simple, non-invasive, real-time tool to enhance patient safety and personalize management during dialysis. Participants will undergo non-invasive ultrasound measurements of carotid corrected flow time (FTc) and peak flow velocity variability (PFVV) during their routine dialysis sessions. These assessments are performed once, one hour after dialysis starts, alongside continuous blood pressure monitoring during the session. No experimental treatments are given, and the study collects data during a single dialysis session lasting up to four hours. During the study, participants will have ultrasound evaluations and blood pressure checks to determine the relationship between FTc, PFVV, and intradialytic hypotension. Researchers will analyze sensitivity, specificity, and optimal cutoff values of these ultrasound parameters using statistical methods. The total involvement includes one dialysis session for ultrasound and blood pressure monitoring, aiming to improve understanding of hypotension risks during hemodialysis.

Predictive Value of Carotid Ultrasonography for Intradialytic Hypotension