Actively Recruiting
Predictive Value of CRP, Albumin, CAR, and mGPS in Treatment Outcomes of DLBCL
Led by Ain Shams University · Updated on 2025-07-10
40
Participants Needed
1
Research Sites
64 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational study evaluates the predictive value of systemic inflammatory markers-CRP, albumin, CRP-to-albumin ratio (CAR), and modified Glasgow Prognostic Score (mGPS)-in patients with diffuse large B-cell lymphoma (DLBCL) receiving R-CHOP chemotherapy. The study examines associations with treatment response, toxicity, and clinical characteristics.
CONDITIONS
Official Title
Predictive Value of CRP, Albumin, CAR, and mGPS in Treatment Outcomes of DLBCL
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 65 years
- Pathologically confirmed, treatment-nave diffuse large B-cell lymphoma (DLBCL)
- Any disease stage (nodal or extra-nodal), with or without B symptoms
- Scheduled to receive standard systemic treatment with R-CHOP chemotherapy
- ECOG performance status between 0 and 2
- Baseline normal complete blood count (CBC), hepatitis viral markers, liver and renal function tests, urine analysis, and echocardiogram
- Additional investigations to rule out current infection if clinically indicated
You will not qualify if you...
- History of other concurrent or previous malignancies
- Relapsed or refractory diffuse large B-cell lymphoma
- Uncontrolled comorbid conditions including diabetes mellitus, autoimmune diseases, active infections, chronic inflammatory diseases, cardiac dysfunction, or liver cell failure
- Pregnant females
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Clinical Oncology and Nuclear Medicine Department, Faculty of Medicine, Ain Shams University
Cairo, Cairo Governorate, Egypt, 1181
Actively Recruiting
Research Team
A
Alaa M Elsayed, MSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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