A Test in Context: D-Dimer.
Jeffrey I Weitz, James C Fredenburgh, John W Eikelboom
https://pubmed.ncbi.nlm.nih.gov/29096812/Actively Recruiting
Led by Al-Nahrain University · Updated on 2025-03-18
112
Participants Needed
1
Research Sites
1 weeks
Total Duration
This research aims to evaluate how well the Modified Caprini Risk Assessment Score combined with D-Dimer levels can predict and help manage lower extremity venous thrombosis LEVT in patients undergoing cardiothoracic surgery in Baghdad. The study focuses on whether using both tools together improves accuracy compared to using each alone and how they can guide prevention and treatment decisions. LEVT, which includes deep vein thrombosis and pulmonary embolism, poses significant risks after surgery, especially within the first six weeks post-operation. Participants will have their LEVT risk assessed using the Modified Caprini Score before surgery and have their D-Dimer blood levels measured after surgery. Depending on the doctors decision, they may receive graduated compression stockings or low-molecular-weight heparin after the procedure. The study observes patients during their hospital stay and follows them up on days 7, 15, and 30 post-discharge to monitor for any venous thromboembolism events or complications. During the study, patients will undergo risk assessments, blood tests, and clinical monitoring to track any episodes of venous thromboembolism, including pulmonary embolism and recurrent deep vein thrombosis. Data collection includes preoperative Caprini scores and postoperative D-Dimer levels. Patients are followed closely during their hospital stay, averaging 7 days, and continue to be monitored for 30 days after discharge to assess outcomes and guide clinical decisions for thrombosis management.
CONDITIONS
Predictive Value of Modified Caprini Score and D-Dimer in Managing Lower Limb Venous Thrombosis in Cardiothoracic Patients
A
Abdul-Ilah R. Khamis
L
Luma K Mohammed, MBChB,FIBMS/CM
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Al-Nahrain University
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for eligibility assessment
Duration - 1 to 2 days around surgery
Participants undergo assessment including the Caprini risk score before surgery and D-dimer testing after surgery to evaluate the risk of lower extremity venous thrombosis.
1 preoperative visit and 1 postoperative visit
Duration - Up to 30 days post-surgery
Participants are observed during their hospital stay and followed up post-discharge to monitor for any episodes of venous thromboembolism or related complications.
In-hospital daily monitoring (average 7 days) and 3 post-discharge visits on Day 7, Day 15, and Day 30
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Lead Sponsor