Actively Recruiting

Age: 18Years +
All Genders
ID06729021

Predictive Efficacy of Modified Caprini Score and D-Dimer for the Evaluation and Management of Lower Extremity Venous Thrombosis Among Cardiothoracic Surgery Patients in Baghdad

Led by Al-Nahrain University · Updated on 2025-03-18

112

Participants Needed

1

Research Sites

1 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate how well the Modified Caprini Risk Assessment Score combined with D-Dimer levels can predict and help manage lower extremity venous thrombosis (LEVT) in patients undergoing cardiothoracic surgery in Baghdad. The study focuses on whether using both tools together improves accuracy compared to using each alone and how they can guide prevention and treatment decisions. LEVT, which includes deep vein thrombosis and pulmonary embolism, poses significant risks after surgery, especially within the first six weeks post-operation. Participants will have their LEVT risk assessed using the Modified Caprini Score before surgery and have their D-Dimer blood levels measured after surgery. Depending on the doctor's decision, they may receive graduated compression stockings or low-molecular-weight heparin after the procedure. The study observes patients during their hospital stay and follows them up on days 7, 15, and 30 post-discharge to monitor for any venous thromboembolism events or complications. During the study, patients will undergo risk assessments, blood tests, and clinical monitoring to track any episodes of venous thromboembolism, including pulmonary embolism and recurrent deep vein thrombosis. Data collection includes preoperative Caprini scores and postoperative D-Dimer levels. Patients are followed closely during their hospital stay, averaging 7 days, and continue to be monitored for 30 days after discharge to assess outcomes and guide clinical decisions for thrombosis management.

CONDITIONS

Brief Title

Predictive Value of Modified Caprini Score and D-Dimer in Managing Lower Limb Venous Thrombosis in Cardiothoracic Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older
  • Hospitalized inpatients with a stay longer than 3 days
  • Provided written informed consent personally or via legal guardian
  • Available for follow-up after surgery to assess outcomes such as LEVT or related complications
Not Eligible

You will not qualify if you...

  • Diagnosed with lower extremity venous thrombosis or pulmonary embolism before the current surgery
  • Having severe bleeding or clotting disorders such as hemophilia or advanced liver disease
  • Receiving any anticoagulation therapy for any reason
  • Did not have a postoperative D-dimer test performed
  • Missing essential clinical or laboratory data for risk score calculation
  • Pregnant women or women within six weeks after giving birth
  • Unable or unwilling to follow the study procedures and follow-up visits

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person) for eligibility assessment

Diagnostic Evaluation

Duration - 1 to 2 days around surgery

Participants undergo assessment including the Caprini risk score before surgery and D-dimer testing after surgery to evaluate the risk of lower extremity venous thrombosis.

1 preoperative visit and 1 postoperative visit

Monitoring

Duration - Up to 30 days post-surgery

Participants are observed during their hospital stay and followed up post-discharge to monitor for any episodes of venous thromboembolism or related complications.

In-hospital daily monitoring (average 7 days) and 3 post-discharge visits on Day 7, Day 15, and Day 30

Trial Site Locations

Total: 1 location

1

College of Medicine - Al-Nahrain University

Baghdad, Iraq

Actively Recruiting

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Research Team

A

Abdul-Ilah R. Khamis

L

Luma K Mohammed, MBChB,FIBMS/CM

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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