Actively Recruiting
Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis
Led by Singapore General Hospital · Updated on 2026-02-27
2200
Participants Needed
3
Research Sites
521 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to identify factors that predict the development of decompensation, acute-on-chronic liver failure (ACLF) and death in patients with liver cirrhosis. Clinical data will be retrieved from existing hospital records. This information may help doctors to identify patients with cirrhosis who are at risk of deterioration earlier (before they develop complications) and to develop effective treatment strategies to prevent or delay these complications. This study is designed as a prospective, non-interventional, observational study. This means that if you agree to participate in the study, you will not be required to undergo any additional hospital visits, tests, procedures or interventions other than the usual standard-of-care management that your doctor will provide. If you consent to participate in this study, you will be providing the study investigators permission to review and analyse your clinical data from the hospital clinical records. Your data will be collected throughout the course of your disease until liver transplantation or death.
CONDITIONS
Official Title
Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with clinical diagnosis of liver cirrhosis
- Age 18 years and above (parental consent required if below 21 years)
- Willing and able to provide informed consent
You will not qualify if you...
- No clinical evidence of liver cirrhosis
- Not willing to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Changi General Hospital
Singapore, Singapore
Actively Recruiting
2
Sengkang General Hospital
Singapore, Singapore
Actively Recruiting
3
Singapore General Hospital
Singapore, Singapore
Actively Recruiting
Research Team
J
Jason Pik Eu Chang, MBBS, MRCP
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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