Actively Recruiting

Age: 18Years +
All Genders
NCT07438288

Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis

Led by Singapore General Hospital · Updated on 2026-02-27

2200

Participants Needed

3

Research Sites

521 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to identify factors that predict the development of decompensation, acute-on-chronic liver failure (ACLF) and death in patients with liver cirrhosis. Clinical data will be retrieved from existing hospital records. This information may help doctors to identify patients with cirrhosis who are at risk of deterioration earlier (before they develop complications) and to develop effective treatment strategies to prevent or delay these complications. This study is designed as a prospective, non-interventional, observational study. This means that if you agree to participate in the study, you will not be required to undergo any additional hospital visits, tests, procedures or interventions other than the usual standard-of-care management that your doctor will provide. If you consent to participate in this study, you will be providing the study investigators permission to review and analyse your clinical data from the hospital clinical records. Your data will be collected throughout the course of your disease until liver transplantation or death.

CONDITIONS

Official Title

Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with clinical diagnosis of liver cirrhosis
  • Age 18 years and above (parental consent required if below 21 years)
  • Willing and able to provide informed consent
Not Eligible

You will not qualify if you...

  • No clinical evidence of liver cirrhosis
  • Not willing to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Changi General Hospital

Singapore, Singapore

Actively Recruiting

2

Sengkang General Hospital

Singapore, Singapore

Actively Recruiting

3

Singapore General Hospital

Singapore, Singapore

Actively Recruiting

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Research Team

J

Jason Pik Eu Chang, MBBS, MRCP

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis | DecenTrialz