Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06291870

Predictors of Post-COVID-19 Clinical and Cognitive Consequences

Led by VA Office of Research and Development · Updated on 2026-01-23

200

Participants Needed

1

Research Sites

206 weeks

Total Duration

On this page

Sponsors

V

VA Office of Research and Development

Lead Sponsor

J

John D. Dingell VA Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical and mental health consequences experienced by some patients. These sequelae may be present four or more weeks after SARS-COV-2 infection, including patients who had initial mild or asymptomatic acute infection. However, there is complete absence of data whether chronic sleep changes due to COVID-19 infection may influence these physical and mental health consequences. While fatigue is one of the common post-COVID conditions, there are no systematic examinations of sleep disturbances in COVID-19 survivors. This will be a pilot observational retrospective and prospective cohort study, to systematically assess if sleep disturbances and severity of sleep apnea comprise a modifiable facet of PASC as well as the short-term and longer-term effects of COVID-19 infection itself on sleep, cognitive function, exercise capacity and lung function.

CONDITIONS

Official Title

Predictors of Post-COVID-19 Clinical and Cognitive Consequences

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals 18 years or older with a prior diagnosis of COVID-19 infection
  • Both genders of all racial and ethnic groups
  • Patients with obstructive sleep apnea (apnea hypopnea index of 5/hour on polysomnography) with or without prior COVID-19 infection for Aim 2
Not Eligible

You will not qualify if you...

  • Inability to give consent
  • Active suicidal symptoms
  • Children of all ages
  • Pregnant women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

John D. Dingell VA Medical Center, Detroit, MI

Detroit, Michigan, United States, 48201-1916

Actively Recruiting

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Research Team

R

Ruchi Rastogi, MS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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