Actively Recruiting
Predictors of Risk in Left Ventricular Non-Compaction
Led by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Updated on 2023-11-01
500
Participants Needed
1
Research Sites
517 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to learn more about the risk factors associated with left ventricular non-compaction (LVNC) and the predictors of adverse outcomes associated with LVNC. The main questions this study aims to answer are as follows. * Are there any genetic mutations that impact the risk of LVNC patients developing ventricular arrhythmias? * Does LV myocardial strain increase risk stratification in the LVNC population with or without genetic mutations? * What are some of the determinants that cause LV dysfunction in LVNC? * What are other risk stratifiers (ex. premature ventricular contraction (PVC) burden on Holter, non-sustained ventricular tachycardia (NSVT) on stress test) that lead to an outcome of ICD implantation? Participants will have their medical records accessed annually for a span of ten years, either prospectively or retrospectively depending on whether they are being actively followed by physicians at the Inherited Arrhythmia Clinic or not, to evaluate LVNC progression over time. This data will be stored in a large clinical registry with the London Heart Rhythm Program at the London Health Sciences Centre, University Hospital Campus.
CONDITIONS
Official Title
Predictors of Risk in Left Ventricular Non-Compaction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have a confirmed diagnosis of left ventricular non-compaction (LVNC) (between 2010-2020 for retrospective patients)
- Be over 18 years of age
You will not qualify if you...
- Have any cardiomyopathy other than LVNC linked to a genetic mutation they carry
- Do not meet one or more of the inclusion criteria
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
London Health Sciences Centre - University Hospital
London, Ontario, Canada, N6A5A5
Actively Recruiting
Research Team
D
Dr. Habib Khan
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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