Actively Recruiting

Age: 18Years +
All Genders
NCT06024759

Predictors of Risk in Left Ventricular Non-Compaction

Led by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Updated on 2023-11-01

500

Participants Needed

1

Research Sites

517 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to learn more about the risk factors associated with left ventricular non-compaction (LVNC) and the predictors of adverse outcomes associated with LVNC. The main questions this study aims to answer are as follows. * Are there any genetic mutations that impact the risk of LVNC patients developing ventricular arrhythmias? * Does LV myocardial strain increase risk stratification in the LVNC population with or without genetic mutations? * What are some of the determinants that cause LV dysfunction in LVNC? * What are other risk stratifiers (ex. premature ventricular contraction (PVC) burden on Holter, non-sustained ventricular tachycardia (NSVT) on stress test) that lead to an outcome of ICD implantation? Participants will have their medical records accessed annually for a span of ten years, either prospectively or retrospectively depending on whether they are being actively followed by physicians at the Inherited Arrhythmia Clinic or not, to evaluate LVNC progression over time. This data will be stored in a large clinical registry with the London Heart Rhythm Program at the London Health Sciences Centre, University Hospital Campus.

CONDITIONS

Official Title

Predictors of Risk in Left Ventricular Non-Compaction

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have a confirmed diagnosis of left ventricular non-compaction (LVNC) (between 2010-2020 for retrospective patients)
  • Be over 18 years of age
Not Eligible

You will not qualify if you...

  • Have any cardiomyopathy other than LVNC linked to a genetic mutation they carry
  • Do not meet one or more of the inclusion criteria

AI-Screening

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Trial Site Locations

Total: 1 location

1

London Health Sciences Centre - University Hospital

London, Ontario, Canada, N6A5A5

Actively Recruiting

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Research Team

D

Dr. Habib Khan

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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