Actively Recruiting

Age: 18Years - 75Years
All Genders
NCT05987631

Predictors of Weight Loss and Metabolic Health After Bariatric Surgery

Led by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Updated on 2023-08-14

1200

Participants Needed

3

Research Sites

240 weeks

Total Duration

On this page

Sponsors

A

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Lead Sponsor

O

Obesitas Kliniek B.V.

Collaborating Sponsor

AI-Summary

What this Trial Is About

In this prospective study the investigators aim to identify preoperative predictors of improvement of metabolic health and weight loss after bariatric surgery focusing on inflammation, insulin sensitivity (in a subgroup of patients), glucoregulatory determinants, psychological traits, feeding behavior characteristics and cardiorespiratory fitness

CONDITIONS

Official Title

Predictors of Weight Loss and Metabolic Health After Bariatric Surgery

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability to provide informed consent
  • Age between 18 and 75 years
  • BMI of 40 kg/m2 or higher, or 35 kg/m2 or higher with obesity-related comorbidity
  • Scheduled for primary bariatric surgery: Roux-en-Y gastric bypass or sleeve gastrectomy
  • Stable weight with less than 10% change in the 3 months before assessment
  • For subgroup: scheduled for Roux-en-Y gastric bypass, insulin resistant (impaired fasting glucose > 5.6 mmol/L or fasting insulin > 74 pmol/L), and postmenopausal women
Not Eligible

You will not qualify if you...

  • Any medical condition except obesity-related issues or well-treated hypothyroidism
  • Pregnancy expected within two years after surgery
  • For subgroup: coagulation disorders or use of anticoagulants
  • Use of medications except statins, antihypertensives (excluding ACE inhibitors or angiotensin receptor blockers), and thyroid hormone
  • Type 2 diabetes mellitus

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Nederlandse Obesitas Kliniek Gouda

Gouda, South Holland, Netherlands, 2803PW

Not Yet Recruiting

2

Nederlandse Obesitas Kliniek Den Haag

The Hague, South Holland, Netherlands, 2591XR

Actively Recruiting

3

Nederlandse Obesitas Kliniek Nieuwegein

Nieuwegein, Utrecht, Netherlands, 3431HK

Not Yet Recruiting

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Research Team

R

Rieneke van der Meer, Drs.

CONTACT

L

Lianda CH Luiijpers, Drs.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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