Actively Recruiting
Preemptive Analgesia for Pain and Anxiety Control in Children With MIH
Led by October University for Modern Sciences and Arts · Updated on 2026-01-28
46
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized, triple-blinded clinical trial aims to evaluate the effect of preemptive analgesia using ibuprofen on pain perception and anxiety during restorative treatment of first permanent molars in children diagnosed with molar-incisor hypomineralization (MIH). MIH-affected teeth often present with hypersensitivity, difficulty in achieving adequate anesthesia, and increased dental anxiety, which complicates dental treatment. Participants aged 6-12 years with MIH will receive either ibuprofen syrup or placebo 30 minutes before treatment. Pain will be assessed using the FLACC Behavioral Pain Scale and Wong-Baker FACES scale, and anxiety will be evaluated through heart rate and oxygen saturation. The results will determine whether preoperative ibuprofen reduces intraoperative pain and improves anxiety control in this population.
CONDITIONS
Official Title
Preemptive Analgesia for Pain and Anxiety Control in Children With MIH
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient with molar incisor hypo-mineralization
- Age between 6 and 12 years old
- Affected tooth shows demarcated opacity with post-eruptive enamel breakdown
- No cavity or prior restorative or preventive treatment related to the defect
You will not qualify if you...
- Children with physical or mental disabilities or medical conditions affecting intervention assessment
- Loss of tooth structure due to caries
- Intolerance to ibuprofen
- Developmental tooth defects such as amelogenesis imperfecta or dentinogenesis imperfecta
AI-Screening
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Trial Site Locations
Total: 1 location
1
October university of modern science and arts
Giza, Egypt, 12611
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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