Actively Recruiting

Age: 18Years - 45Years
FEMALE
NCT06339749

Pregnancy Outcomes in Normotensive VS stage1 Hypertension: a Prospective Observational Study

Led by FANG HE · Updated on 2024-07-03

626

Participants Needed

1

Research Sites

96 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In 2017, the American College of Cardiology (ACC) and American Heart Association (AHA) guidelines built on evidence that elevated blood pressure increases cardiovascular mortality in the general population, Reclassification of BP; however, these diagnostic definitions do not include pregnant women, and whether newly diagnosed stage 1 hypertension affects pregnancy complications remains unclear. In this study, the combination of maternal factors, MAP and PLGF was used to comprehensively analyze the risk factors of preeclampsia through the "Bayesian rule" developed by the British Fetal Medicine Foundation (FMF). According to the guidelines and consensus, the pregnant women were considered to be at high risk when the calculated risk was higher than 1% of the population. To compare the pregnancy outcomes of women with normal blood pressure in the first trimester and stage 1 hypertension in different risk groups, and to find out whether screening for preeclampsia can be omitted for women with normal blood pressure in the first trimester, while screening for preeclampsia should still be performed for women with stage 1 hypertension as an independent moderate risk factor, and finally to optimize the screening strategy for preeclampsia.

CONDITIONS

Official Title

Pregnancy Outcomes in Normotensive VS stage1 Hypertension: a Prospective Observational Study

Who Can Participate

Age: 18Years - 45Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Single live fetus with normal nuchal translucency at 11-14+1 weeks of gestation
  • Blood pressure below 140/90 mmHg before 14+1 weeks of gestation
  • Plan to have prenatal examinations and delivery at the study hospital
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Chronic hypertension
  • Type 1 or type 2 diabetes
  • Kidney disease
  • Autoimmune disease

AI-Screening

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Trial Site Locations

Total: 1 location

1

FANG HE

Guangzhou, Guangdong, China, 510150

Actively Recruiting

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Research Team

F

Fang He, M.D

CONTACT

Y

Yafei Wang, Master

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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