Pilot Study of a Multimodal Prehabilitation Program During Chemotherapy Before Pancreatic Cancer Surgery

What this Trial Is About

Researchers are evaluating a structured prehabilitation program for adults with pancreatic cancer who are receiving chemotherapy before planned surgery. The study aims to see if patients can participate in and stick to this program, which targets improving physical fitness, nutrition, and symptom control. It is a single-center, prospective pilot study designed to explore the feasibility and patient experience during this period. Participants will receive a multimodal prehabilitation program integrated into their routine preoperative care while undergoing neoadjuvant chemotherapy. This program includes supervised, personalized exercise training, nutritional assessment and counseling with recommended immunonutrition, and supportive care focused on symptom management and functional support. The intervention continues from the start of chemotherapy until the planned surgery. During the study, assessments will be done at baseline, after completing the prehabilitation period before surgery, and about one month post-surgery. These include standardized fitness tests, patient surveys, and clinical data review to measure participation, adherence, physical function changes, nutritional status, quality of life, and postoperative outcomes. The study will last approximately up to 14 months from enrollment to capture recovery and follow-up data.

Prehab for Pancreatic Cancer Surgery